NEWS
Warm congratulation on Huanan Wang's (王华南) achievement of Pd-catalyzed axially chiral allenyl phosphonate syntheses!

Chiral organophosphorous compounds are very important in catalysis, organic syntheses, and medicinal chemistry. However, catalytic enantioselective protocols for the axially chiral allenyl phosphorous compounds have never been reported. Herein, a palladium-catalyzed enantioselective carbon-phosphorous bond formation reaction affording axially chiral allenyl phosphonates has been developed. The reaction enjoys high yields and ee accommodating a wide range of functional groups. Mechanistic studies have unveiled an overwhelming kinetic resolution process. Link!